A meta-analysis of 11 studies found that a single dose of JYNNEOS vaccine, containing a 78.23% estimated efficacy rate, can protect recipients from mpox infection. However, more research and ongoing surveillance are needed to understand the reasons behind breakthrough infections and improve immunization strategies for better protection against mpox. The findings highlight the need for further research and surveillance.

A meta-analysis reveals open laparoscopic cholecystectomy offers quicker access to the pneumoperitoneum but has higher risks of complications like gas leakage and wound infection, requiring careful evaluation.

A study of 7130 Middle East and North African Healthcare Professionals (HCPs) found high rates of cardiovascular disease (CVD) and risk factors such as smoking, alcohol, and smoking. Nutritionists were the most active, with 45.3% walking 150 minutes or more per week. This highlights the need for improved health behavior among HCPs.

A study in five UAE physiotherapy clinics found that age, education, and radiographic lumbar spine alignment significantly impacted conservative therapy outcomes in patients with lumbar herniated nucleus pulposus (HNP). Younger age, less education, and better coronal radiological lumbar spine alignment significantly impacted the likelihood of success in 6-month outcomes.

The study investigates variations in VEGF-A/B gene expression following SARS-CoV MA15 disease initiation. Results show significant differences in TNF, VEGF-A, and VEGF-B expression between groups and over time. The study suggests that VEGF-A exhibits a more consistent response to SARS MA15 infection, despite the limited specificity of standard inflammatory biomarkers.

The study provides important insights into the molecular mechanisms and potential diagnostic biomarkers and therapeutic targets for Kawasaki disease.

This review examines the challenges faced by Pediatric Emergency Departments in low- and middle-income countries in managing infectious diseases, emphasizing the need for integrated approaches.

Neurodegenerative diseases like Parkinson's and Alzheimer's cause neuron loss, affecting motor and cognitive functions. Lipid-based nanocarriers may improve brain targeting and ease BBB transportation, but no authorized nanoformulas target the CNS. Challenges include safety, formula availability, and reliable evidence.

This meta-analysis compared AI models and clinicians in detecting hepatocellular carcinoma. Results showed high sensitivity and specificity for RCNN models, while AI-assisted contrast-enhanced ultrasound models had poor accuracy. Faster R-CNN models excel in image classification and data extraction.

The study assesses depression, anxiety, and stress levels among the healthcare workforce in the Middle East and North Africa (MENA) region during the COVID-19 pandemic. The study involved 4,845 healthcare workers from 11 countries. The prevalence of depression was 70.9, anxiety was 70.9, and stress was 61.4. The study highlights the significant impact of the pandemic on healthcare workers.

The COVID-19 pandemic severely impacted the MENA region's labor force, leading to significant job losses and health issues. Work attendance dropped significantly, and many workers did not take necessary measures. The study suggests that COVID-19 may have intensified inequalities, emphasizing the need to monitor and reverse this decline.

This study explores perceptions of vaccine effectiveness in rural and urban communities across various countries. Results show 64% agree the vaccine effectively controls viral spread, with 23% believing there's no need for vaccination. Understanding these determinants is crucial for effective COVID-19 prevention and transmission.

This study evaluated the epidemiological and clinical characteristics of acute kidney injury (AKI) among 80 cancer patients in Egypt. Results showed AKI was more prevalent among elderly females with solid tumors, with common symptoms including vomiting, fatigue, anorexia, electrolyte imbalances, and hypovolemia.

A study conducted in ten Arab countries found that 62.7% of participants practiced self-medication during the COVID-19 pandemic. The most commonly used drugs were analgesics, antipyretics, and vitamins. Factors leading to self-medication included experience with similar health conditions, urgency of the problem, and older age. Pharmacist consultation was the most common source of information.

The study examining Libya's attitudes towards COVID-19 vaccines found that confidence, constraints, calculation, and collective responsibility were significantly different between vaccine acceptors and rejectors. Older age, being male, having confidence, and collective responsibility positively affected vaccination, while working in crafts and related trade work negatively affected vaccination.

A study comparing the efficacy of two doses of Evusheld, a combination of tixagevimab and cilgavimab, as prophylaxis and treatment for immunocompromised patients, found no significant difference in infection rates, mortality rates, or hospitalization rates compared to the 300 mg dose. However, Evusheld 600 mg showed a significant decrease in infection rates and mortality rates. Further trials are needed to compare the two doses.

A retrospective observational study at Almaza Fever Egyptian Hospital found that demographic features, clinical characteristics, laboratory parameters, and pharmacological treatment received by elderly patients with Covid-19 were predictors of mortality. Predictors like male sex, age, and hospital stay positively associated with deterioration of laboratory measures and biomarkers, indicating the importance of early patient identification.

Melatonin has been found to be beneficial in COVID-19 prevention and treatment, with a higher clinical improvement rate and lower mortality rate in patients taking it. Melatonin also reduced CRP levels and hospital stay length, resulting in shorter recovery times and shorter mechanical ventilation duration.

This systematic review and meta-analysis reveals that 45,926 people (56.14%) were willing to receive Mpox vaccination, while 28.94% were unwilling. Females and homosexuals were found to be less willing. Vaccination is crucial for preventing Mpox infection and fostering immunity, and targeted educational programs can help.

This meta-analysis reveals that co-infection with HIV and mpox increases hospitalization and mortality rates. The study found that individuals with both conditions have a higher risk of severe disease and death due to immunosuppression caused by HIV. The findings emphasize the need for early diagnosis, prompt treatment initiation, and effective management strategies for people living with HIV and mpox.

A systematic review of randomized controlled trials found that oxytocin, a neuropeptide hormone, did not significantly impact hyperphagia or weight in patients with Prader-Willi Syndrome (PWS). The study suggests that further large-sample trials are needed to establish the effectiveness of oxytocin in PWS patients.

This review examines the success rate and efficacy of cryoballoon ablation in patients with atrial fibrillation and heart failure with reduced ejection fraction. Results showed that cryoablation reduced AF recurrence and improved clinical outcomes, with a 3% mortality rate. The study included six studies.

The study compared the efficacy and safety of nonvitamin K antagonist oral anticoagulants (NOACs) versus warfarin in atrial fibrillation (AF) patients with morbid obesity. Results showed a lower risk of major bleeding events in NOAC patients compared to warfarin patients. However, some outcomes were not significantly different, indicating the need for future research.

The study reveals an increase in anabolic hormones and nutritional supplements use among regular exercisers in the Middle East and North Africa (MENA) region during the COVID-19 lockdown. The majority of participants were male, with a higher level of knowledge in medical fields or sports coaching. The study suggests increasing awareness of the harmful effects of unsupervised use of these substances.

This study assesses digital health literacy's relevance to COVID-19 vaccination. A cross-sectional survey found that urban respondents had higher intention for vaccination than rural respondents. Factors such as country, education, employment, and income were associated with vaccination intention. Priority should be given to improving DHL and vaccination awareness programs targeting rural areas, lower education levels, lower income, and unemployed groups.

A study investigating the expression levels of seven circulating vascular-related RNA transcripts found that they could serve as potential CAD biomarkers, reflecting cellular vascular function, proliferation, and inflammatory processes in CAD patients. The study suggests that blood transcriptome analysis opens new frontiers for non-invasive diagnosis of CAD, preventing plaque rupture and sudden death.

This systematic review and meta-analysis investigates the associations between Celiac disease (CD) and psychiatric disorders, specifically anxiety and depression. Results show CD patients are at a higher risk of developing anxiety and depression symptoms. GFD adherence may decrease anxiety and depression levels, but further studies are needed.

A cross-sectional study found that a small proportion of participants in the Middle East and North Africa (MENA) region, particularly Egypt and Saudi Arabia, have moderate knowledge and poor attitudes towards clinical trials. Education and residence were identified as determinants of participants' knowledge and attitudes.

A study conducted in 20 countries found that most adults believe vaccination is effective in controlling and preventing COVID-19. Factors such as age, education, and income were associated with vaccine effectiveness, acceptance, and hesitancy. The study suggests these factors should be considered in developing COVID-19 vaccination campaigns to boost uptake.

Although the study demonstrated better decrease in BMI with RSG, this needs to be further investigated due to the small population included in analyses (182 for 6-months & 417 for 1-year). Conversely, LSG showed better outcomes in LOS, readmission, leak, conversion, & reoperation rates , cost & surgery duration. However, mortality and bleeding rates were similar amongst the two groups. Hence, LSG seems to be superior to RSG according to the available literature. Yet, better evidence can only be derived from future RCTs.